SCHEMBL2492142

SCHEMBL2492142

O=c1cc(O)c2cc(F)ccc2o1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.64
CA12 O43570 2/20 0.59
CA1 P00915 2/20 0.59
CA9 Q16790 2/20 0.59
KMT2A Q03164 3/20 0.53
ALDH1A1 P00352 3/20 0.53
KDM4E B2RXH2 2/20 0.53
NQO1 P15559 2/20 0.53
GABRP O00591 3/20 0.47
GABRD O14764 3/20 0.47
GABRA1 P14867 3/20 0.47
GABRB1 P18505 3/20 0.47
GABRG2 P18507 3/20 0.47
GABRB3 P28472 3/20 0.47
GABRA5 P31644 3/20 0.47
GABRA3 P34903 3/20 0.47
GABRA2 P47869 3/20 0.47
GABRB2 P47870 3/20 0.47
GABRA4 P48169 3/20 0.47
GABRE P78334 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31621885 1.00 PIM1 (0.64) PIM1CA12CA1CA9KMT2A
SCHEMBL2761833 0.85 ALDH1A1 (0.68) PIM1CA12CA1CA9KMT2A
SCHEMBL29716542 0.85 ALDH1A1 (0.68) PIM1CA12CA1CA9KMT2A
SCHEMBL5341818 0.81 KDM4E (0.72) PIM1CA12CA1CA9KMT2A
SCHEMBL14424526 0.81 GABRP (0.50) PIM1CA12CA1CA9KMT2A
SCHEMBL15842598 0.81 GABRP (0.50) PIM1CA12CA1CA9KMT2A
SCHEMBL23640323 0.78 ALDH1A1 (0.50) PIM1CA12CA1CA9KMT2A
SCHEMBL10603419 0.78 ALDH1A1 (0.60) CA12CA1CA9KMT2AALDH1A1
SCHEMBL2761544 0.78 PIM1 (1.00) PIM1CA12CA1CA9KMT2A
SCHEMBL2490464 0.78 PIM1 (0.64) PIM1CA12CA1CA9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120165029-A All-solid-state lithium metal battery and preparation method thereof 中国科学院上海高等研究院 2025-06-17 CN claimed
CN-112517060-B Catalyst, application and synthesis method of 4-hydroxycoumarin derivative 山东农业大学 2022-03-25 CN claimed
CN-112517060-A Catalyst, application and synthesis method of 4-hydroxycoumarin derivative 山东农业大学 2021-03-19 CN claimed
CN-103372012-B Application of theanine in preparing product for preventing and treating cancer 张国营 2016-12-14 CN claimed
CN-103372012-A Application of theanine in preparing product for preventing and treating cancer ZHANG GUOYING 2013-10-30 CN claimed
CN-102846598-A Application of coumarin in preparing formation inhibitors of advanced glycation end products (AGEs) GUANGZHOU KANGCHENG PHARMACEUTICAL RES CO LTD 2013-01-02 CN claimed
CN-120165029-A All-solid-state lithium metal battery and preparation method thereof 中国科学院上海高等研究院 2025-06-17 CN disclosed
CN-119192119-A Coumarin thioether pleuromutilin derivative and application thereof 西华大学 2024-12-27 CN disclosed
CN-115057850-B Aloe-emodin derivative and preparation method and application thereof 中国医学科学院药用植物研究所 2023-11-10 CN disclosed
CN-116621801-A Coumarin derivative and preparation method and application thereof 暨南大学 2023-08-22 CN disclosed
CN-115057850-A Aloe-emodin derivative and preparation method and application thereof 中国医学科学院药用植物研究所 2022-09-16 CN disclosed
WO-2022128832-A1 OPTICALLY ACTIVE DEVICES MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed
CN-112517060-B Catalyst, application and synthesis method of 4-hydroxycoumarin derivative 山东农业大学 2022-03-25 CN disclosed
CN-1053921-A Therapeutical agent BOOTS CO PLC (GB) 1991-08-21 CN disclosed
WO-1991011448-A1 THERAPEUTIC AGENTS THE BOOTS COMPANY PLC (GB) 1991-08-08 WO disclosed
WO-1990001481-A1 THERAPEUTIC AGENTS THE BOOTS COMPANY PLC (GB) 1990-02-22 WO disclosed
EP-0354693-A1 Therapeutic agents The Boots Company PLC (GB) 1990-02-14 EP disclosed
US-3993670-A OPTICAL BRIGHTENERS BAYER AKTIENGESELLSCHAFT (DT) 1976-11-23 US disclosed
US-3971731-A OPTICAL BRIGHTENER, UV ABSORBER BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed
US-3968119-A OPTICAL BRIGHTENERS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-06 US disclosed