Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | BID | P55957 | 3/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.32 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.32 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.32 |
| ▸ | MPL | P40238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944703 | 0.89 | STAT3 (0.40) | STAT3STAT1SIRT1 | |
| SCHEMBL29910098 | 0.88 | STAT3 (0.39) | STAT3STAT1 | |
| SCHEMBL5133634 | 0.85 | STAT3 (0.42) | STAT3STAT1SIRT1 | |
| SCHEMBL4551743 | 0.85 | STAT3 (0.44) | STAT3STAT1SIRT1 | |
| SCHEMBL3720959 | 0.84 | STAT3 (0.37) | STAT3STAT1 | |
| SCHEMBL3520094 | 0.84 | STAT3 (0.41) | STAT3STAT1 | |
| SCHEMBL6003904 | 0.84 | STAT3 (0.41) | STAT3STAT1 | |
| SCHEMBL3522373 | 0.84 | STAT3 (0.41) | STAT3STAT1 | |
| SCHEMBL15510967 | 0.84 | STAT3 (0.41) | STAT3STAT1 | |
| SCHEMBL7647119 | 0.84 | STAT3 (0.41) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038823-A1 | BETA-SUBSTITUTED PORPHYRINS | MASSEY UNIVERSITY (NZ) | 2006-04-13 | — | — | WO | disclosed |