Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24303010 | 1.00 | L3MBTL1 (0.41) | L3MBTL1HTTCA2ADRB2HRH3 | |
| SCHEMBL24303428 | 1.00 | L3MBTL1 (0.41) | L3MBTL1HTTCA2ADRB2HRH3 | |
| SCHEMBL24303004 | 0.68 | MEN1 (0.41) | L3MBTL1HTTCA2KDM4E | |
| SCHEMBL23640237 | 0.68 | MEN1 (0.41) | L3MBTL1HTTCA2KDM4E | |
| SCHEMBL23640517 | 0.66 | TAAR1 (0.33) | — | |
| SCHEMBL23640445 | 0.65 | — | — | |
| SCHEMBL24302321 | 0.65 | — | — | |
| SCHEMBL24302268 | 0.64 | — | — | |
| SCHEMBL23640229 | 0.64 | — | — | |
| SCHEMBL14273361 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848367-A1 | TRICYCLIC COMPOUNDS ACTING ON CRBN PROTEINS | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2021-07-14 | — | — | EP | disclosed |