Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24303004 | 1.00 | MEN1 (0.41) | MEN1KMT2AHPGDMAPK1ALDH1A1 | |
| SCHEMBL14434736 | 0.76 | HPGD (0.40) | MEN1KMT2AHPGDMAPK1ALDH1A1 | |
| SCHEMBL23640241 | 0.75 | MAPK14 (0.39) | KMT2AALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL24302888 | 0.75 | MAPK14 (0.39) | KMT2AALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL13220406 | 0.74 | TSHR (0.33) | HTTCA12CA1CA2CA7 | |
| SCHEMBL24303428 | 0.68 | L3MBTL1 (0.41) | HTTCA2KDM4EL3MBTL1 | |
| SCHEMBL23640528 | 0.68 | L3MBTL1 (0.41) | HTTCA2KDM4EL3MBTL1 | |
| SCHEMBL24303010 | 0.68 | L3MBTL1 (0.41) | HTTCA2KDM4EL3MBTL1 | |
| SCHEMBL23640279 | 0.68 | MTNR1A (0.46) | HPGDMAPK1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL24302330 | 0.68 | MTNR1A (0.46) | HPGDMAPK1ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848367-A1 | TRICYCLIC COMPOUNDS ACTING ON CRBN PROTEINS | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2021-07-14 | — | — | EP | disclosed |