Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8821847 | 0.97 | TP53 (0.43) | TP53HTTALDH1A1KDM4EMEN1 | |
| SCHEMBL7918982 | 0.91 | TP53 (0.43) | TP53HTTALDH1A1KDM4EMEN1 | |
| SCHEMBL29853674 | 0.88 | TP53 (0.45) | TP53HTTALDH1A1KDM4EMEN1 | |
| SCHEMBL2317562 | 0.88 | TP53 (0.45) | TP53HTTALDH1A1KDM4EMEN1 | |
| SCHEMBL9576844 | 0.85 | TP53 (0.40) | TP53HTTALDH1A1KDM4EMEN1 | |
| SCHEMBL6917217 | 0.83 | ALDH1A1 (0.40) | TP53HTTALDH1A1KDM4EMEN1 | |
| SCHEMBL11765896 | 0.83 | ACHE (0.35) | TP53HTTALDH1A1KDM4EMEN1 | |
| SCHEMBL3731188 | 0.82 | TP53 (0.41) | TP53HTTALDH1A1KDM4EMEN1 | |
| SCHEMBL8613100 | 0.79 | TP53 (0.40) | TP53HTTALDH1A1KDM4EMEN1 | |
| SCHEMBL9576729 | 0.79 | GCGR (0.37) | TP53HTTALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2528864-A1 | METHOD OF PRODUCING CYCLOHEXASILANE COMPOUNDS | Ndsu Research Foundation (US) | 2012-12-05 | — | — | EP | disclosed |
| WO-2011094191-A1 | METHOD OF PRODUCING CYCLOHEXASILANE COMPOUNDS | NDSU RESEARCH FOUNDATION (US) | 2011-08-04 | — | — | WO | disclosed |