SCHEMBL8821847

SCHEMBL8821847

CCc1c(CC)c(CC)c2ccccc2c1CC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.43
HTT P42858 2/20 0.42
ALDH1A1 P00352 6/20 0.39
KDM4E B2RXH2 4/20 0.39
MEN1 O00255 1/20 0.39
TNNI3 P19429 1/20 0.39
TNNT2 P45379 1/20 0.39
TNNC1 P63316 1/20 0.39
KMT2A Q03164 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
CYP1A2 P05177 2/20 0.38
TSHR P16473 2/20 0.37
LMNA P02545 1/20 0.37
KIF11 P52732 1/20 0.35
NCEH1 Q6PIU2 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MAPK1 P28482 1/20 0.35
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL2364100 0.97 TP53 (0.41) TP53HTTALDH1A1KDM4EMEN1
SCHEMBL7918982 0.94 TP53 (0.43) TP53HTTALDH1A1KDM4EMEN1
SCHEMBL29853674 0.90 TP53 (0.45) TP53HTTALDH1A1KDM4EMEN1
SCHEMBL2317562 0.90 TP53 (0.45) TP53HTTALDH1A1KDM4EMEN1
SCHEMBL9576844 0.87 TP53 (0.40) TP53HTTALDH1A1KDM4EMEN1
SCHEMBL6917217 0.85 ALDH1A1 (0.40) TP53HTTALDH1A1KDM4EMEN1
SCHEMBL11765896 0.85 ACHE (0.35) TP53HTTALDH1A1KDM4EMEN1
SCHEMBL3731188 0.85 TP53 (0.41) TP53HTTALDH1A1KDM4EMEN1
SCHEMBL8613100 0.82 TP53 (0.40) TP53HTTALDH1A1KDM4EMEN1
SCHEMBL9576729 0.82 GCGR (0.37) TP53HTTALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9301899-A None JP disclosed
CN-108699076-A Naphtho- indacene 1,4-Dithiapentalene and polymer 巴斯夫欧洲公司 2018-10-23 CN disclosed
CN-102753517-A Process for preparing polyalkylated oligoalkylenepolyamines NDSU RES FOUNDATION 2012-10-24 CN disclosed
JP-H09301899-A PRODUCTION OF POLYCYCLIC AROMATIC COMPOUND NISSAN CHEM IND LTD 1997-11-25 JP disclosed
CN-1029611-C Process for producing alkyl-substituted aromatic hydrocarbons MITSUI PETROCHEMICAL IND (JP) 1995-08-30 CN disclosed
US-5254766-A Alkylation MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-10-19 US disclosed
CN-1060833-A The production method of alkyl-substituted aromatic hydrocarbon MITSUI PETROCHEMICAL IND (JP) 1992-05-06 CN disclosed
EP-0481360-A2 Process for producing alkyl-substituted aromatic hydrocarbon MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-04-22 EP disclosed
US-5030784-A Process for converting lower-alkyl substituted aromatic compounds and butadiene to 4-aryl-1-butene or 4-aryl-1-pentene and propylene SHELL OIL COMPANY (US) 1991-07-09 US disclosed