Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.37 |
| ▸ | GNPAT | O15228 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333422 | 0.80 | ALDH1A1 (0.44) | ALDH1A1ENPEPTSHRPLA2G10GABRP | |
| SCHEMBL2329130 | 0.79 | PLA2G10 (0.46) | ALDH1A1ENPEPPLA2G10FOLH1GNPAT | |
| SCHEMBL15543759 | 0.78 | ENPEP (0.46) | ALDH1A1ENPEPTSHRPLA2G10FOLH1 | |
| SCHEMBL29242708 | 0.78 | ENPEP (0.46) | ALDH1A1ENPEPTSHRPLA2G10FOLH1 | |
| SCHEMBL2327522 | 0.77 | ENPEP (0.40) | ALDH1A1ENPEPPLA2G10GNPATGABRP | |
| SCHEMBL2363939 | 0.77 | CYP2D6 (0.55) | ALDH1A1ENPEPTSHRPLA2G10FOLH1 | |
| SCHEMBL2335269 | 0.76 | ENPEP (0.39) | ALDH1A1ENPEPPLA2G10FOLH1GNPAT | |
| SCHEMBL15313039 | 0.74 | PLA2G2C (0.60) | ALDH1A1TSHRPLA2G10PLA2G2C | |
| SCHEMBL27826930 | 0.73 | ENPEP (0.48) | ALDH1A1ENPEPTSHRFOLH1GABRP | |
| SCHEMBL2330572 | 0.73 | GABRP (0.45) | ALDH1A1ENPEPTSHRPLA2G10FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095218-A1 | TEMPLATE-FIXED PEP TIDOMIME TICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2011-08-11 | — | — | WO | disclosed |