Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL27515739 | 0.80 | — | — | |
| Thiourea SCHEMBL8046111 | 0.77 | — | — | |
| Guanidine SCHEMBL687217 | 0.75 | — | — | |
| Acetamide SCHEMBL27363690 | 0.74 | — | — | |
| Nitrous Acid SCHEMBL17180228 | 0.74 | — | — | |
| Nitrous Acid SCHEMBL8933907 | 0.73 | — | — | |
| Guanidine SCHEMBL29883323 | 0.73 | — | — | |
| Nitrous Acid SCHEMBL19743130 | 0.73 | ALDH1A1 (0.75) | — | |
| Nitrous Acid SCHEMBL9079679 | 0.73 | ALDH1A1 (1.00) | — | |
| Nitrous Acid SCHEMBL11219505 | 0.73 | ALDH1A1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2360471-A1 | METHOD FOR PRE-TREATING SAMPLE CONTAINING GLYCOSYLATED HEMOGLOBIN | Sekisui Medical Co., Ltd. (JP) | 2011-08-24 | — | — | EP | disclosed |