Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23911988 | 0.89 | ALDH1A1 (0.47) | TP53LMNATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL23911979 | 0.88 | LMNA (0.43) | TP53MEN1KMT2ALMNATHRB | |
| SCHEMBL22591707 | 0.85 | TP53 (0.49) | TP53MEN1KMT2ALMNATHRB | |
| SCHEMBL30486819 | 0.85 | TP53 (0.49) | TP53MEN1KMT2ALMNATHRB | |
| SCHEMBL27060609 | 0.81 | TP53 (0.52) | TP53MEN1KMT2ALMNATHRB | |
| SCHEMBL22337503 | 0.80 | TP53 (0.51) | TP53MEN1KMT2ATHRBTSHR | |
| SCHEMBL30486800 | 0.80 | TP53 (0.51) | TP53MEN1KMT2ATHRBTSHR | |
| SCHEMBL22337322 | 0.80 | TP53 (0.51) | TP53MEN1KMT2ATHRBTSHR | |
| SCHEMBL23642722 | 0.80 | MEN1 (0.61) | MEN1KMT2ALMNAALDH1A1L3MBTL1 | |
| SCHEMBL23642606 | 0.77 | TP53 (0.46) | TP53MEN1KMT2ALMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368523-B1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-07-14 | — | — | EP | disclosed |