Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23642631 | 0.88 | TP53 (0.49) | LMNAPKMTHRBKMT2AMEN1 | |
| SCHEMBL23911988 | 0.82 | ALDH1A1 (0.47) | LMNAALDH1A1TSHREPHX2TP53 | |
| SCHEMBL23642722 | 0.78 | MEN1 (0.61) | LMNAHCRTR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL22591707 | 0.76 | TP53 (0.49) | LMNAPKMTHRBKMT2AMEN1 | |
| SCHEMBL23642720 | 0.76 | MEN1 (0.62) | HTTKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL30486819 | 0.76 | TP53 (0.49) | LMNAPKMTHRBKMT2AMEN1 | |
| SCHEMBL908389 | 0.71 | OPRD1 (0.33) | KMT2AALDH1A1TSHRGAATP53 | |
| SCHEMBL22337322 | 0.71 | TP53 (0.51) | PKMTHRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL22337785 | 0.71 | ALDH1A1 (0.38) | LMNAALDH1A1GAAEPHX2TP53 | |
| SCHEMBL22337503 | 0.71 | TP53 (0.51) | PKMTHRBKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601263-B1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-10-13 | — | — | EP | disclosed |