SCHEMBL7181082

SCHEMBL7181082

CN1C(=O)C(F)=C(F)C1=O

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 2/20 0.35
GSK3B P49841 2/20 0.35
MGLL Q99685 1/20 0.35
CASP3 P42574 1/20 0.35
ALDH1A1 P00352 2/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6850987 0.76 GSK3A (0.44) GSK3AGSK3BMGLLCASP3ALDH1A1
SCHEMBL12869405 0.69 CASP3 (0.31) CASP3MAPT
SCHEMBL802733 0.67 ALDH1A1 (0.40) GSK3AGSK3BMGLLCASP3ALDH1A1
SCHEMBL2378877 0.64 GSK3A (0.35) GSK3AGSK3BMGLLCASP3ALDH1A1
SCHEMBL22342866 0.64 ALDH1A1 (0.35) GSK3AGSK3BMGLLCASP3ALDH1A1
SCHEMBL9926467 0.64 KMT2A (0.35) GSK3AGSK3BMGLLCASP3ALDH1A1
SCHEMBL11414636 0.64 GSK3A (0.35) GSK3AGSK3BMGLLCASP3ALDH1A1
SCHEMBL407513 0.64 BLM (0.42) GSK3AGSK3BMGLLCASP3ALDH1A1
SCHEMBL19506068 0.64 GSK3A (0.35) GSK3AGSK3BMGLLCASP3ALDH1A1
SCHEMBL1163642 0.64 GSK3A (0.35) GSK3AGSK3BMGLLCASP3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213267-A1 EXTREME HIGH TEMPERATURE STABLE ADHESIVES AND COATINGS DESIGNER MOLECULES, INC 2022-07-07 US disclosed
WO-2020215025-A1 EXTREME HIGH TEMPERATURE STABLE ADHESIVES AND COATINGS DESIGNER MOLECULES, INC (US) 2020-10-22 WO disclosed
US-6579658-B2 Fluorinated maleic anhydride or maleimide SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-06-17 US disclosed
US-20010038969-A1 Novel polymers, resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. OF (JP) 2001-11-08 US disclosed