Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615143 | 0.89 | EPHX2 (0.59) | KIF11KMT2APPARAFFAR1 | |
| SCHEMBL24510476 | 0.83 | MAOB (0.48) | TAAR1MAOBHDAC1HDAC8IDO1 | |
| SCHEMBL3335304 | 0.82 | IDO1 (0.58) | TAAR1MAOBKIF11IDO1KMT2A | |
| SCHEMBL29151897 | 0.81 | KIF11 (0.54) | MAOBKIF11KMT2APPARDPPARA | |
| SCHEMBL28561124 | 0.81 | TAAR1 (0.57) | TAAR1LMNAMAOBHDAC1HDAC8 | |
| SCHEMBL16244411 | 0.80 | LMNA (0.53) | TAAR1LMNAMAOBIDO1NR3C2 | |
| SCHEMBL22752009 | 0.80 | PPARA (0.44) | TAAR1MAOBHDAC1HDAC8KMT2A | |
| SCHEMBL22857498 | 0.80 | PPARA (0.47) | TAAR1MAOBHDAC1HDAC8KMT2A | |
| SCHEMBL28904903 | 0.80 | SCN8A (0.48) | MAOBKIF11HDAC1HDAC8KMT2A | |
| SCHEMBL28322474 | 0.79 | THRB (0.46) | TAAR1HDAC1HDAC8PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358702-A2 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK Holdings Co., Ltd. (KR) | 2011-08-24 | — | — | EP | disclosed |