Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394450 | 1.00 | LMNA (0.52) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2364394 | 0.90 | LMNA (0.68) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1710460 | 0.89 | ALDH1A1 (0.47) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL16209877 | 0.86 | TSHR (0.57) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10841725 | 0.86 | TSHR (0.57) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10841183 | 0.86 | TSHR (0.57) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL7849811 | 0.86 | TSHR (0.57) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10401825 | 0.86 | TSHR (0.57) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2124312 | 0.86 | TSHR (0.57) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1937969 | 0.86 | TSHR (0.57) | LMNAALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563337-B1 | CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE | SALAMA ZOSER B (DE) | 2017-07-26 | — | — | EP | disclosed |
| EP-2563337-A1 | CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE | Salama, Zoser B. (DE) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011134675-A1 | CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE | SALAMA ZOSER B (DE) | 2011-11-03 | — | — | WO | disclosed |