SCHEMBL23645508

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30291301	1.00	SIGMAR1 (0.39)	SIGMAR1CYP3A4CYP2C9CYP2C19RECQL
	SCHEMBL30291320	0.78	OPRM1 (0.41)	SIGMAR1CYP2C9CYP2C19OPRM1OPRL1
	SCHEMBL23668800	0.78	OPRM1 (0.41)	SIGMAR1CYP2C9CYP2C19OPRM1OPRL1
	SCHEMBL23645063	0.78	OPRM1 (0.38)	SIGMAR1CYP3A4CYP2C19OPRM1OPRL1
	SCHEMBL30291417	0.78	CYP3A4 (0.36)	CYP3A4CYP2C9CYP2C19RECQLNPSR1
	SCHEMBL23645522	0.77	OPRM1 (0.40)	SIGMAR1CYP2C9CYP2C19OPRM1OPRL1
	SCHEMBL30291243	0.77	OPRM1 (0.40)	SIGMAR1CYP2C9CYP2C19OPRM1OPRL1
	SCHEMBL23644320	0.76	OPRM1 (0.39)	SIGMAR1CYP2C9CYP2C19OPRM1OPRL1
	SCHEMBL30291422	0.76	OPRM1 (0.39)	SIGMAR1CYP2C9CYP2C19OPRM1OPRL1
	SCHEMBL23645494	0.75	HDAC4 (0.41)	SIGMAR1OPRM1OPRL1DPP4CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.