Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GCG | P01275 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2362953 | 0.84 | HPGD (0.52) | HPGDCNR1NPC1RAB9AMEN1 | |
| SCHEMBL8744815 | 0.73 | GAA (0.56) | NPC1RAB9AALDH1A1KDM4EHTT | |
| SCHEMBL11167030 | 0.72 | POLB (0.58) | HPGDCNR1EPHX2MAPTALDH1A1 | |
| SCHEMBL9289218 | 0.71 | CSNK2A2 (0.66) | HPGDCNR1NPC1RAB9AALDH1A1 | |
| SCHEMBL23792060 | 0.71 | ALDH1A1 (0.51) | HPGDNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL2394244 | 0.70 | CSNK2A2 (0.47) | CNR1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9890719 | 0.70 | KMT2A (0.49) | HPGDNPC1RAB9ATSHRMAPT | |
| SCHEMBL5007251 | 0.70 | PTGER1 (0.47) | HPGDNPC1TSHRMAPTALDH1A1 | |
| SCHEMBL9833523 | 0.70 | MAPT (0.51) | HPGDRAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL1064811 | 0.69 | EPHX2 (0.79) | HPGDEPHX2NPC1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349999-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | Universität des Saarlandes (DE) | 2011-08-03 | — | — | EP | disclosed |