Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13191460 | 0.92 | — | — | |
| SCHEMBL13284205 | 0.77 | MAP4K4 (0.45) | ACHEMAPTENPP3CYP2C9 | |
| SCHEMBL3287696 | 0.76 | ACHE (0.73) | ACHETDP1KIF11MCL1ALDH1A1 | |
| SCHEMBL197731 | 0.76 | ACHE (0.73) | ACHETDP1KIF11MCL1ALDH1A1 | |
| SCHEMBL18661495 | 0.76 | ACHE (0.73) | ACHETDP1KIF11MCL1ALDH1A1 | |
| SCHEMBL9925867 | 0.76 | ACHE (0.44) | ACHETDP1KIF11MCL1L3MBTL1 | |
| SCHEMBL7785235 | 0.76 | ALDH1A1 (0.50) | TDP1KIF11ALDH1A1HPGDKDM4E | |
| SCHEMBL26725099 | 0.76 | ALDH1A1 (0.50) | TDP1KIF11ALDH1A1HPGDKDM4E | |
| SCHEMBL20083331 | 0.74 | CYP1A2 (0.48) | KIF11L3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL16882937 | 0.74 | BCL2L1 (0.44) | ACHECA2CES2CES1LPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615027-B1 | METHODS OF USE FOR TRISUBSTITUTED BENZOTRIAZOLE DERIVATIVES AS DIHYDROOROTATE OXYGENASE INHIBITORS | AURIGENE DISCOVERY TECH LTD (IN) | 2021-07-14 | — | — | EP | disclosed |