Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903114 | 0.91 | — | — | |
| SCHEMBL13002373 | 0.83 | ACHE (0.44) | ACHETDP1ALDH1A1CA1CA2 | |
| SCHEMBL3287696 | 0.78 | ACHE (0.73) | ACHETDP1ENPP3ENPP1KIF11 | |
| SCHEMBL18661495 | 0.78 | ACHE (0.73) | ACHETDP1ENPP3ENPP1KIF11 | |
| SCHEMBL197731 | 0.78 | ACHE (0.73) | ACHETDP1ENPP3ENPP1KIF11 | |
| SCHEMBL14643579 | 0.78 | ALDH1A1 (0.50) | TDP1KIF11ALDH1A1CA1CA2 | |
| SCHEMBL14492415 | 0.78 | ALDH1A1 (0.50) | TDP1KIF11ALDH1A1CA1CA2 | |
| SCHEMBL23645554 | 0.76 | ACHE (0.42) | ACHETDP1ENPP3ENPP1KIF11 | |
| SCHEMBL13862559 | 0.76 | APP (0.31) | — | |
| SCHEMBL12334415 | 0.76 | ALDH1A1 (0.48) | ALDH1A1CA2CA9ALOX15GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1618087-B1 | ANTIBACTERIAL AGENTS | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2012-06-13 | — | — | EP | disclosed |