SCHEMBL2364576

SCHEMBL2364576

C=CCNN(CC=C)CCCCC

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.39
TSHR P16473 2/20 0.38
ALDH1A1 P00352 2/20 0.36
DNM1 Q05193 3/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9423866 0.89 FAAH (0.42) FAAHTSHRALDH1A1DNM1ZDHHC20
SCHEMBL5823693 0.86 TSHR (0.37) FAAHTSHRALDH1A1DNM1ZDHHC20
SCHEMBL170586 0.79 SMN1; SMN2 (0.32)
SCHEMBL7681528 0.79 FAAH (0.39) FAAHTSHRALDH1A1DNM1ZDHHC20
SCHEMBL5365307 0.79 FAAH (0.36) FAAHTSHRALDH1A1DNM1
Hydrochloric Acid SCHEMBL28784380 0.77 SMN1; SMN2 (0.31)
SCHEMBL4551351 0.77 TSHR (0.39) FAAHTSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL15477589 0.75 TSHR (0.43) FAAHTSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL11617998 0.75 TSHR (0.35) FAAHTSHRALDH1A1
SCHEMBL3674964 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8008274-B2 P1-(2′-deoxycytidine 5′-)P4-(uridine 5′-)tetraphosphate, tetra-(alkali metal) salt, for treating sinusitis INSPIRE PHARMACEUTICALS, INC. (US) 2011-08-30 US disclosed
US-20090306010-A1 P1-(2'-DEOXYCYTIDINE 5'-)P4-(URIDINE 5'-)TETRAPHOSPHATE, TETRA-(ALKALI METAL) SALT, FOR TREATING DISORDERS MERCK SHARP & DOHME CORP. 2009-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306010-A1 P1-(2'-DEOXYCYTIDINE 5'-)P4-(URIDINE 5'-)TETRAPHOSPHATE, TETRA-(ALKALI METAL) SALT, FOR TREATING DISORDERS P2RY1, P2RY4, P2RY2 FAAH 4225/4885TSHR 490/4885ALDH1A1 1771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.