Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28784380 | 0.97 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL20440769 | 0.79 | CYP1A2 (0.30) | — | |
| SCHEMBL2364576 | 0.79 | FAAH (0.39) | — | |
| SCHEMBL3674964 | 0.77 | — | — | |
| SCHEMBL16654852 | 0.77 | — | — | |
| SCHEMBL1685448 | 0.74 | TSHR (0.30) | — | |
| SCHEMBL8656915 | 0.72 | — | — | |
| SCHEMBL17226154 | 0.72 | — | — | |
| SCHEMBL11617998 | 0.72 | TSHR (0.35) | — | |
| SCHEMBL11134053 | 0.72 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 499 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023230217-A1 | ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-11-30 | — | — | WO | claimed |
| US-20230381142-A1 | ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-11-30 | — | — | US | claimed |
| CN-112334468-A | Quinoline compounds, their preparation and use as antimalarial agents | 美国卫生和人力服务部 | 2021-02-05 | — | — | CN | claimed |
| US-20170355695-A1 | SMYD Inhibitors | Epizyme, Inc. (US) | 2017-12-14 | — | — | US | claimed |
| EP-2430013-B1 | HETEROARYL COMPOUNDS AS PIKK INHIBITORS | AMGEN INC (US) | 2014-10-15 | — | — | EP | claimed |
| US-20130317028-A1 | C5aR ANTAGONISTS | CHEMOCENTRYX, INC. (US) | 2013-11-28 | — | — | US | claimed |
| EP-2308874-B1 | Bridged monobactams useful as beta-lactamase inhibitors | BASILEA PHARMACEUTICA AG (CH) | 2013-01-23 | — | — | EP | claimed |
| US-20120190666-A1 | Heteroaryl Compounds as PIKK Inhibitors | AMGEN INC. (US) | 2012-07-26 | — | — | US | claimed |
| EP-2430013-A1 | HETEROARYL COMPOUNDS AS PIKK INHIBITORS | Amgen, Inc (US) | 2012-03-21 | — | — | EP | claimed |
| EP-2027086-B1 | N-BENZOYL-PYRROLIDIN-3-YLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH LLC (US) | 2011-11-16 | — | — | EP | claimed |
| WO-1986003749-A1 | BICYCLIC HETEROARYL THIAZOLE COMPOUNDS, CARDIOTONIC COMPOSITIONS INCLUDING THE SAME, AND THEIR USES | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1986-07-03 | — | — | WO | claimed |
| US-4529602-A | Sulfodehydroabietic acid compound | TANABE SEIYAKU CO., LTD. (JP) | 1985-07-16 | — | — | US | claimed |
| EP-0066241-B1 | MODIFIED CIS-1,4-POLYISOPRENE RUBBER, A PROCESS FOR ITS MANUFACTURE, A VULCANIZED MODIFIED CIS-1,4-POLYISOPRENE RUBBER COMPOSITION AND THE USE OF THE MODIFIED CIS-1,4-POLYISOPRENE RUBBER FOR PREPARING VULCANIZED SHAPED ARTICLES | KURARAY CO., LTD. (JP) | 1985-05-08 | — | — | EP | claimed |
| EP-0119050-A2 | Dihydropyridine anti-ischaemic and antihypertensive agents | Pfizer Limited (GB) | 1984-09-19 | — | — | EP | claimed |
| US-4446281-A | Modified cis-1,4-polyisoprene rubber, a process for manufacturing the same, and a composition containing the same | KURARAY CO., LTD. (JP) | 1984-05-01 | — | — | US | claimed |
| EP-0066241-A2 | Modified cis-1,4-polyisoprene rubber, a process for its manufacture, a vulcanized modified cis-1,4-polyisoprene rubber composition and the use of the modified cis-1,4-polyisoprene rubber for preparing vulcanized shaped articles | KURARAY CO., LTD. (JP) | 1982-12-08 | — | — | EP | claimed |
| EP-0013727-B1 | PREPARATION OF (THIO)HYDANTOINS AND THEIR APPLICATION AS HEAT-RESISTANT COATINGS, FILMS, POWDERS, ADHESIVES, MOULDED PRODUCTS, LACQUERS AND FIBRES | BAYER AG (DE) | 1982-04-07 | — | — | EP | claimed |
| EP-0016565-A1 | 1,2,4-Triazole derivatives, processes for their production and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1980-10-01 | — | — | EP | claimed |
| US-4225588-A | POLYCYCLIC NITROGEN-CONTAINING COMPOUNDS AS POTENTIATORS FOR BLEOMYCINS OR PHLEOMYCINS | COMMONWEALTH SCIENTIFIC & INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1980-09-30 | — | — | US | claimed |
| EP-0005782-A1 | Plant growth regulants and compositions containing them, their application and their preparation | BAYER AG (DE) | 1979-12-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381142-A1 | ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF | MPO, SSB, SGMS2 | SMN1; SMN2 4698/4885 |
| US-20130317028-A1 | C5aR ANTAGONISTS | C5AR1, C5AR2, C3AR1 | SMN1; SMN2 2376/4885 |
| US-20120190666-A1 | Heteroaryl Compounds as PIKK Inhibitors | PIK3CA, PIKFYVE, PIK3CD | SMN1; SMN2 3999/4885 |
| US-20170355695-A1 | SMYD Inhibitors | SMYD3, SMYD2, SMURF2 | SMN1; SMN2 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.