SCHEMBL28232162

SCHEMBL28232162

Clc1ccc2c(c1)Nc1ccccc1S2.[KH]

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 12/20 0.96
BCHE P06276 3/20 0.96
ACHE P22303 3/20 0.96
MAPT P10636 6/20 0.63
GAA P10253 5/20 0.63
MEN1 O00255 3/20 0.63
KMT2A Q03164 3/20 0.63
SNCA P37840 3/20 0.63
ALOX15 P16050 2/20 0.63
TDP1 Q9NUW8 2/20 0.63
CYP1A2 P05177 1/20 0.63
POLB P06746 1/20 0.63
CYP3A4 P08684 1/20 0.63
ADORA3 P0DMS8 1/20 0.63
ALOX12 P18054 1/20 0.63
MAOA P21397 1/20 0.63
CNR1 P21554 1/20 0.63
PTGS1 P23219 1/20 0.63
SLC6A2 P23975 1/20 0.63
HTR2C P28335 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29384266 0.98 NOX1 (1.00) NOX1BCHEACHEMAPTGAA
SCHEMBL236458 0.98 NOX1 (1.00) NOX1BCHEACHEMAPTGAA
SCHEMBL28679021 0.96 NOX1 (0.96) NOX1BCHEACHEMAPTGAA
SCHEMBL1509893 0.90 NOX1 (0.84) NOX1BCHEACHEMAPTGAA
SCHEMBL28117966 0.88 NOX1 (0.81) NOX1BCHEACHEMAPTGAA
SCHEMBL4670416 0.87 NOX1 (0.79) NOX1BCHEACHEMAPTGAA
Urea SCHEMBL27590816 0.87 NOX1 (0.79) NOX1BCHEACHEMAPTGAA
SCHEMBL30769670 0.87 NOX1 (0.79) NOX1BCHEACHEMAPTGAA
SCHEMBL239261 0.87 NOX1 (0.79) NOX1BCHEACHEMAPTGAA
SCHEMBL28117917 0.85 NOX1 (0.76) NOX1BCHEACHEMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108530384-B Preparation method of prochlorperazine 南京泽恒医药技术开发有限公司 2021-12-28 CN claimed
CN-108530384-B Preparation method of prochlorperazine 南京泽恒医药技术开发有限公司 2021-12-28 CN disclosed
CN-108530384-A A kind of preparation method of prochlorperazine 南京泽恒医药技术开发有限公司 2018-09-14 CN disclosed