Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.76 |
| ▸ | ESR1 | P03372 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | STS | P08842 | 3/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 2/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.58 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2712915 | 1.00 | LMNA (0.76) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| SCHEMBL10715585 | 1.00 | LMNA (0.76) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| SCHEMBL2713500 | 1.00 | LMNA (0.76) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| SCHEMBL23645593 | 1.00 | LMNA (0.76) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| SCHEMBL13015302 | 0.87 | LMNA (0.77) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| SCHEMBL10079788 | 0.87 | LMNA (0.77) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| SCHEMBL9593672 | 0.86 | LMNA (0.72) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| SCHEMBL9417521 | 0.86 | LMNA (0.72) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| Estradiol Methyl Ether SCHEMBL6464173 | 0.86 | HSD17B10 (1.00) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| Estradiol Methyl Ether SCHEMBL23645792 | 0.86 | HSD17B10 (1.00) | LMNAHSD17B10ESR1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2625190-B1 | DERIVATIVES OF STEROID BENZYLAMINES, HAVING AN ANTIPARASITIC, ANTIBACTERIAL, ANTIMYCOTIC AND/OR ANTIVIRAL ACTION | UNIV JUSTUS LIEBIG GIESSEN (DE) | 2021-07-14 | — | — | EP | disclosed |