Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | ESR1 | P03372 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | PGR | P06401 | 2/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 2/20 | 0.62 |
| ▸ | AR | P10275 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10079788 | 1.00 | LMNA (0.77) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| SCHEMBL17808696 | 0.87 | LMNA (0.60) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| SCHEMBL2713500 | 0.87 | LMNA (0.76) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| Estradiol Methyl Ether SCHEMBL6464173 | 0.87 | HSD17B10 (1.00) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| SCHEMBL19961981 | 0.87 | ESR1 (0.77) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| Estradiol Methyl Ether SCHEMBL23645792 | 0.87 | HSD17B10 (1.00) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| SCHEMBL23645808 | 0.87 | LMNA (0.76) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| SCHEMBL23645593 | 0.87 | LMNA (0.76) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| Estradiol Methyl Ether SCHEMBL18686406 | 0.87 | HSD17B10 (1.00) | LMNAHSD17B10ESR1SMN1; SMN2MAPT | |
| SCHEMBL2712915 | 0.87 | LMNA (0.76) | LMNAHSD17B10ESR1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9416383-B2 | Method for enhancing catalytic activity of a lipase | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2016-08-16 | — | — | US | disclosed |
| US-20100330628-A1 | ACTIVATED LIPASES AND METHODS OF USE THEREFOR | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2010-12-30 | — | — | US | disclosed |