Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30497699 | 1.00 | ALDH1A1 (0.59) | ALDH1A1 | |
| SCHEMBL23645894 | 0.86 | ALDH1A1 (0.60) | ALDH1A1 | |
| SCHEMBL30497717 | 0.86 | ALDH1A1 (0.57) | ALDH1A1 | |
| SCHEMBL23666146 | 0.86 | ALDH1A1 (0.57) | ALDH1A1 | |
| SCHEMBL30754321 | 0.85 | ALDH1A1 (0.56) | ALDH1A1 | |
| SCHEMBL30497701 | 0.85 | ALDH1A1 (0.56) | ALDH1A1 | |
| SCHEMBL23645956 | 0.85 | ALDH1A1 (0.56) | ALDH1A1 | |
| SCHEMBL23645887 | 0.85 | ALDH1A1 (0.56) | ALDH1A1 | |
| SCHEMBL23666092 | 0.85 | ALDH1A1 (0.64) | ALDH1A1 | |
| SCHEMBL23645923 | 0.84 | ALDH1A1 (0.53) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11897865-B2 | ABHD12 inhibitors and methods of making and using same | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-02-13 | — | — | US | disclosed |
| EP-3793552-B1 | ABHD12 INHIBITORS AND METHODS OF MAKING AND USING SAME | SCRIPPS RESEARCH INST (US) | 2023-07-12 | — | — | EP | disclosed |
| EP-3793552-B1 | ABHD12 INHIBITORS AND METHODS OF MAKING AND USING SAME | SCRIPPS RESEARCH INST (US) | 2023-07-12 | — | — | EP | disclosed |
| US-20210221790-A1 | ABHD12 INHIBITORS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2021-07-22 | — | — | US | disclosed |
| US-20210221790-A1 | ABHD12 INHIBITORS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11897865-B2 | ABHD12 inhibitors and methods of making and using same | ABHD12, SAMHD1, ABHD11 | ALDH1A1 2729/4885 |
| US-20210221790-A1 | ABHD12 INHIBITORS AND METHODS OF MAKING AND USING SAME | ABHD12, SAMHD1, ABHD11 | ALDH1A1 2729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.