SCHEMBL2364594

SCHEMBL2364594

CC(O)(OCC(F)(F)F)Oc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 2/20 0.35
PDK2 Q15119 2/20 0.35
PDK3 Q15120 2/20 0.35
PDK4 Q16654 2/20 0.35
MEN1 O00255 1/20 0.35
S1PR2 O95136 1/20 0.35
S1PR4 O95977 1/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
XBP1 P17861 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
PAX8 Q06710 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
S1PR3 Q99500 1/20 0.35
S1PR5 Q9H228 1/20 0.35
PPARG P37231 4/20 0.34
CCR6 P51684 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6040935 0.79 LTA4H (0.39) MEN1LMNAGAAKMT2ANPSR1
SCHEMBL675061 0.78 CA4 (0.43) PDK1PDK2PDK3PDK4MEN1
Fluoride SCHEMBL5185114 0.76 CA4 (0.42) PDK1PDK2PDK3PDK4MEN1
SCHEMBL11147766 0.74 PPARG (0.47) GAAPPARGPPARA
SCHEMBL10586931 0.72 CA4 (0.44) PDK1PDK2PDK3PDK4MEN1
SCHEMBL11018055 0.69 PPARG (0.37) LMNAKMT2APPARGPPARAALDH1A1
SCHEMBL8566517 0.69 ALDH1A1 (0.46) MEN1LMNAKMT2ATACR1ALDH1A1
SCHEMBL9770338 0.69 CA4 (0.43) PDK1PDK2PDK3PDK4PPARG
SCHEMBL693241 0.69 CA4 (0.43) PDK1PDK2PDK3PDK4MEN1
SCHEMBL10477060 0.69 CA4 (0.43) PDK1PDK2PDK3PDK4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012147107-A2 NOVEL & IMPROVED PROCESSES FOR THE PREPARATION OF INDOLINE DERIVATIVES AND ITS PHARMACEUTICAL COMPOSITION MSN LABORATORIES LIMITED (IN) 2012-11-01 WO disclosed
WO-2011101864-A1 NOVEL PROCESS FOR THE SYNTHESIS OF PHENOXYETHYL DERIVATIVES PANACEA BIOTEC LTD (IN) 2011-08-25 WO disclosed