Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370351 | 0.86 | KIF11 (0.46) | ALDH1A1PPARGPPARA | |
| SCHEMBL10477060 | 0.84 | CA4 (0.43) | CA4TSHRLTA4HMAPK1ALDH1A1 | |
| SCHEMBL13039942 | 0.80 | CA4 (0.40) | CA4TSHRLTA4HMAPK1ALDH1A1 | |
| SCHEMBL821312 | 0.80 | CA4 (0.40) | CA4TSHRLTA4HMAPK1ALDH1A1 | |
| SCHEMBL20003172 | 0.80 | CA4 (0.40) | CA4TSHRLTA4HMAPK1ALDH1A1 | |
| SCHEMBL17107524 | 0.80 | LMNA (0.58) | PPARGPPARASLC6A2L3MBTL1 | |
| SCHEMBL15372299 | 0.79 | MAPT (0.47) | TSHRALDH1A1SLC6A2L3MBTL1KCNH2 | |
| SCHEMBL4224012 | 0.78 | CA4 (0.48) | CA4TSHRLTA4HMAPK1ALDH1A1 | |
| SCHEMBL168125 | 0.78 | KIF11 (0.47) | TSHRLTA4HGRIN2BSLC6A2CCR6 | |
| SCHEMBL93074 | 0.78 | CA4 (0.48) | CA4TSHRLTA4HMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271953-A1 | Novel compounds for treatment of diseases related to DUX4 expression | Facio Intellectual Property B.V. (NL) | 2023-08-31 | — | — | US | disclosed |
| EP-3442961-B1 | AGRICULTURAL CHEMICALS | REDAG CROP PROT LTD (GB) | 2021-03-24 | — | — | EP | disclosed |
| WO-2018102358-A1 | METHODS OF TREATING OR PREVENTING COGNITIVE IMPAIRMENT USING INDANE ACETIC ACID DERIVATIVES BASED ON APOE4 GENOTYPE | T3D THERAPEUTICS, INC. (US) | 2018-06-07 | — | — | WO | disclosed |
| WO-2017178819-A1 | AGRICULTURAL CHEMICALS | REDAG CROP PROTECTION LTD (GB) | 2017-10-19 | — | — | WO | disclosed |
| CN-104379574-B | For suppressing the heterocyclic carbamate derivatives of the activity of ABL1, ABL2 and BCR ABL1 | 诺华股份有限公司 | 2017-03-01 | — | — | CN | disclosed |
| US-20160031890-A1 | NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR INHIBITION OF ROS | GRUENEBERG, Dorre A. | 2016-02-04 | — | — | US | disclosed |
| EP-2604612-A1 | C-ARYL GLUCOSIDE DERIVATIVES, PREPARATION RPOCESS AND PHARMACEUTICAL USE THEREOF | Shanghai Hengrui Pharmaceutical Co. Ltd. (CN) | 2013-06-19 | — | — | EP | disclosed |
| US-8268531-B2 | Photoacid generator compounds and compositions | CORNELL RESEARCH FOUNDATION, INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-20110008732-A1 | PHOTOACID GENERATOR COMPOUNDS AND COMPOSITIONS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| US-7824839-B2 | cationic lactone containing perfluorinated sulfonate or sulfonimides with iodonium or sulfonium anions as photoacid generator, a polyhydroxystyrene homo or copolymer and a solvent (propylene glycol/1,2-/, monoalkyl ether, ethyl lactone ); semiconductor, heat exposure, pattern forming; development | CORNELL RESEARCH FOUNDATION, INC. (US) | 2010-11-02 | — | — | US | disclosed |
| US-20090136868-A1 | PHOTOACID GENERATOR COMPOUNDS AND COMPOSITIONS | CORNELL RESEARCH FOUNDATION, INC. | 2009-05-28 | — | — | US | disclosed |
| US-4981836-A | Recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271953-A1 | Novel compounds for treatment of diseases related to DUX4 expression | UTRN, ZFX, CBX6 | CA4 3935/4885TSHR 3539/4885LTA4H 3497/4885 |
| US-20090136868-A1 | PHOTOACID GENERATOR COMPOUNDS AND COMPOSITIONS | ASIC1, PPA1, PPOX | CA4 562/4885TSHR 3707/4885LTA4H 2278/4885 |
| US-20160031890-A1 | NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR INHIBITION OF ROS | ROS1, NOX4, NOX1 | CA4 1518/4885TSHR 4141/4885LTA4H 3556/4885 |
| US-20110008732-A1 | PHOTOACID GENERATOR COMPOUNDS AND COMPOSITIONS | ASIC1, PPA1, PPOX | CA4 562/4885TSHR 3707/4885LTA4H 2278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.