SCHEMBL23646252

SCHEMBL23646252

O=C(O)CCCCCCCCCCCCCNC(=O)NC1CCC(F)(F)CC1

nearest known ligand 0.69

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 11/20 0.69
EPHX2 P34913 6/20 0.60
PRMT1 Q99873 1/20 0.53
ALOX5 P09917 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23646225 1.00 EPHX1 (0.69) EPHX1EPHX2PRMT1ALOX5
SCHEMBL23646204 1.00 EPHX1 (0.69) EPHX1EPHX2PRMT1ALOX5
SCHEMBL23646256 1.00 EPHX1 (0.69) EPHX1EPHX2PRMT1ALOX5
SCHEMBL1065387 0.82 EPHX1 (1.00) EPHX1EPHX2
SCHEMBL1066578 0.82 EPHX1 (1.00) EPHX1EPHX2
SCHEMBL15741883 0.82 EPHX1 (1.00) EPHX1EPHX2
SCHEMBL28612121 0.82 EPHX1 (1.00) EPHX1EPHX2
SCHEMBL4009806 0.81 EPHX1 (0.46) EPHX1EPHX2
SCHEMBL23646186 0.79 EPHX1 (0.73) EPHX1EPHX2PRMT1
SCHEMBL23646241 0.79 EPHX1 (0.73) EPHX1EPHX2PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12258324-B2 Fatty acid analogues and methods of use LIN BIOSCIENCE INC. (TW) 2025-03-25 US disclosed
US-20210221781-A1 FATTY ACID ANALOGUES AND METHODS OF USE LIN BIOSCIENCE INC. (TW) 2021-07-22 US disclosed
US-20210221781-A1 FATTY ACID ANALOGUES AND METHODS OF USE LIN BIOSCIENCE INC. (TW) 2021-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210221781-A1 FATTY ACID ANALOGUES AND METHODS OF USE ELOVL1, FADS1, ALOX5 EPHX1 1873/4885EPHX2 2379/4885PRMT1 4275/4885
US-12258324-B2 Fatty acid analogues and methods of use ELOVL1, FADS1, ALOX5 EPHX1 1873/4885EPHX2 2379/4885PRMT1 4275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.