Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364653 | 0.78 | MTNR1A (0.46) | CYP1A2HTTLMNAL3MBTL1CNR1 | |
| SCHEMBL877680 | 0.78 | POLB (0.43) | POLBCYP2C19RECQLKDM4ETSHR | |
| SCHEMBL27466589 | 0.75 | CYP1A2 (0.50) | CYP1A2CYP2C19KDM4ETSHRHTT | |
| SCHEMBL3433832 | 0.71 | CYP1A2 (0.54) | CYP1A2CYP2C19TSHRHTTLMNA | |
| SCHEMBL6691407 | 0.70 | CYP1A2 (0.48) | CYP1A2CYP2C19RECQLTSHRKMT2A | |
| SCHEMBL6688205 | 0.70 | CYP1A2 (0.48) | CYP1A2CYP2C19RECQLTSHRKMT2A | |
| SCHEMBL27508355 | 0.70 | SCN5A (0.46) | CYP1A2HTTNPC1ALDH1A1RAB9A | |
| SCHEMBL1133623 | 0.70 | SCN5A (0.46) | CYP1A2HTTNPC1ALDH1A1RAB9A | |
| SCHEMBL877143 | 0.70 | MMP13 (0.40) | POLBRECQLKDM4ETSHRHTT | |
| SCHEMBL27602921 | 0.69 | CYP1A2 (0.47) | CYP1A2CYP2C19TSHRHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |