Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL236415 | 0.98 | EPHX1 (0.44) | HTTEPHX1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL233212 | 0.90 | HTT (0.40) | HTTEPHX1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL233157 | 0.89 | EPHX1 (0.41) | HTTEPHX1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL234319 | 0.78 | ALDH1A1 (0.39) | EPHX1KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL233393 | 0.76 | ALDH1A1 (0.43) | EPHX1KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL232293 | 0.73 | ALDH1A1 (0.33) | HTTEPHX1ALDH1A1GAA | |
| SCHEMBL235312 | 0.73 | ALDH1A1 (0.39) | EPHX1KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL234434 | 0.73 | ALDH1A1 (0.33) | HTTEPHX1ALDH1A1GAA | |
| SCHEMBL231385 | 0.73 | ALDH1A1 (0.39) | EPHX1KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL233443 | 0.72 | EPHX1 (0.40) | EPHX1KDM4EALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2360190-B1 | SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME | TOHO TITANIUM CO LTD (JP) | 2015-10-14 | — | — | EP | disclosed |
| US-8426537-B2 | Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same | TOHO TITANIUM CO., LTD. (JP) | 2013-04-23 | — | — | US | disclosed |
| US-20120004378-A1 | SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME | TOHO TITANIUM CO., LTD (JP) | 2012-01-05 | — | — | US | disclosed |
| EP-2360190-A1 | SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME | Toho Titanium CO., LTD. (JP) | 2011-08-24 | — | — | EP | disclosed |