Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL233212 | 0.98 | HTT (0.40) | EPHX1HTTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL236415 | 0.91 | EPHX1 (0.44) | EPHX1HTTKDM4EMEN1KMT2A | |
| SCHEMBL236480 | 0.89 | HTT (0.43) | EPHX1HTTKDM4EMEN1KMT2A | |
| SCHEMBL236425 | 0.78 | ALDH1A1 (0.41) | EPHX1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL234475 | 0.78 | ALDH1A1 (0.41) | EPHX1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL236569 | 0.78 | ALDH1A1 (0.41) | EPHX1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL236193 | 0.76 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL234304 | 0.76 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL234199 | 0.76 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL235066 | 0.73 | ADH1B (0.32) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2360190-B1 | SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME | TOHO TITANIUM CO LTD (JP) | 2015-10-14 | — | — | EP | disclosed |
| US-8426537-B2 | Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same | TOHO TITANIUM CO., LTD. (JP) | 2013-04-23 | — | — | US | disclosed |
| US-20120004378-A1 | SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME | TOHO TITANIUM CO., LTD (JP) | 2012-01-05 | — | — | US | disclosed |
| EP-2360190-A1 | SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME | Toho Titanium CO., LTD. (JP) | 2011-08-24 | — | — | EP | disclosed |