SCHEMBL236415

SCHEMBL236415

CC(C)CN[Si](NC1CCCCC1)(NC1CCCCC1)NC1CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.44
HTT P42858 2/20 0.42
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MMP1 P03956 1/20 0.33
MMP8 P22894 1/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
SHBG P04278 1/20 0.31
ANPEP P15144 2/20 0.30
ERAP2 Q6P179 2/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL236480 0.98 HTT (0.43) EPHX1HTTKDM4EMEN1KMT2A
SCHEMBL233157 0.91 EPHX1 (0.41) EPHX1HTTKDM4EMEN1KMT2A
SCHEMBL233212 0.89 HTT (0.40) EPHX1HTTKDM4EALDH1A1CYP1A2
SCHEMBL233393 0.79 ALDH1A1 (0.43) EPHX1KDM4EALDH1A1HSD17B10SMN1; SMN2
SCHEMBL234319 0.76 ALDH1A1 (0.39) EPHX1KDM4EMEN1KMT2AALDH1A1
SCHEMBL236117 0.74 ALDH1A1 (0.43) EPHX1KDM4EALDH1A1HSD17B10SMN1; SMN2
SCHEMBL234949 0.74 ALDH1A1 (0.38) EPHX1KDM4EALDH1A1CYP3A4HSD17B10
SCHEMBL234421 0.74 ALDH1A1 (0.43) EPHX1KDM4EALDH1A1HSD17B10SMN1; SMN2
SCHEMBL236464 0.74 ALDH1A1 (0.38) EPHX1KDM4EALDH1A1CYP3A4HSD17B10
SCHEMBL232041 0.73 EPHX1 (0.43) EPHX1KDM4EMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed