Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30041346 | 0.91 | NOS3 (0.34) | HCRTR1HCRTR2NUDT1 | |
| SCHEMBL14926090 | 0.91 | NOS3 (0.34) | HCRTR1HCRTR2NUDT1 | |
| Bromide SCHEMBL23649800 | 0.86 | NUDT1 (0.32) | HCRTR1HCRTR2NUDT1 | |
| SCHEMBL1828405 | 0.75 | NOS3 (0.37) | NUDT1 | |
| SCHEMBL23649498 | 0.72 | NOS3 (0.39) | NUDT1 | |
| SCHEMBL1092751 | 0.70 | ALOX15 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL31493074 | 0.68 | TAAR1 (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL22903513 | 0.68 | SYK (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL1420222 | 0.67 | NOS3 (0.47) | — | |
| SCHEMBL27691144 | 0.67 | SCN9A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288264-A1 | MAP4K1 INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2021146370-A1 | MAP4K1 INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2021-07-22 | — | — | WO | disclosed |