Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23636536 | 0.95 | ALDH1A1 (0.35) | ALDH1A1HDAC3HDAC1ARDRD2 | |
| SCHEMBL23636549 | 0.86 | ALDH1A1 (0.36) | ALDH1A1ARKMT2AAGERCA9 | |
| SCHEMBL23636552 | 0.86 | ALDH1A1 (0.36) | ALDH1A1ARKMT2AMAP2K1TLR9 | |
| SCHEMBL31398729 | 0.84 | AR (0.43) | ALDH1A1ARKMT2AMAP2K1TLR9 | |
| SCHEMBL23636547 | 0.84 | AR (0.43) | ALDH1A1ARKMT2AMAP2K1TLR9 | |
| SCHEMBL31398730 | 0.83 | ALDH1A1 (0.34) | ALDH1A1ARCA9 | |
| SCHEMBL23651261 | 0.83 | ALDH1A1 (0.34) | ALDH1A1ARCA9 | |
| SCHEMBL23636541 | 0.80 | ALDH1A1 (0.36) | ALDH1A1ARKMT2AMAP2K1TLR9 | |
| SCHEMBL23651257 | 0.78 | ALDH1A1 (0.35) | ALDH1A1AR | |
| SCHEMBL23651256 | 0.78 | ALDH1A1 (0.36) | ALDH1A1ARKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11067566-B2 | Photochromic xanthene fluorophores and their utility live-cell beyond the diffraction limit | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2021-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11067566-B2 | Photochromic xanthene fluorophores and their utility live-cell beyond the diffraction limit | XPA, ANXA5, KIF20A | ALDH1A1 3826/4885HDAC3 3112/4885HDAC1 4057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.