Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | AGER | Q15109 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23636547 | 1.00 | AR (0.43) | ARALDH1A1MAP2K1HSD17B3KMT2A | |
| SCHEMBL23636541 | 0.90 | ALDH1A1 (0.36) | ARALDH1A1MAP2K1HSD17B3KMT2A | |
| SCHEMBL23651240 | 0.90 | AR (0.42) | ARALDH1A1MAP2K1HSD17B3KMT2A | |
| SCHEMBL23651239 | 0.90 | AR (0.42) | ARALDH1A1MAP2K1HSD17B3KMT2A | |
| SCHEMBL23636552 | 0.84 | ALDH1A1 (0.36) | ARALDH1A1MAP2K1KMT2AAGER | |
| SCHEMBL23636536 | 0.84 | ALDH1A1 (0.35) | ARALDH1A1MAP2K1HSD17B3KMT2A | |
| SCHEMBL23651249 | 0.84 | ALDH1A1 (0.35) | ARALDH1A1MAP2K1HSD17B3KMT2A | |
| SCHEMBL23636531 | 0.83 | CA12 (0.40) | ARALDH1A1HSD17B3KMT2ATLR9 | |
| SCHEMBL23636549 | 0.82 | ALDH1A1 (0.36) | ARALDH1A1KMT2AAGERCA9 | |
| SCHEMBL31398730 | 0.79 | ALDH1A1 (0.34) | ARALDH1A1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250012787-A1 | Photochromic xanthene fluorophores and their utility in live-cell imaging beyond the diffraction limit | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2025-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250012787-A1 | Photochromic xanthene fluorophores and their utility in live-cell imaging beyond the diffraction limit | XPA, KIF20A, KIF20B | AR 4880/4885ALDH1A1 3914/4885MAP2K1 4794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.