SCHEMBL2365126

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12439736	0.94	MAPK1 (0.41)	JAK2JAK3TRPV1KDRCYP11B2
	SCHEMBL13968290	0.94	MET (0.37)	BRAFJAK2JAK3PTK2MET
	SCHEMBL12440239	0.90	MET (0.40)	JAK2JAK3METKDRCYP11B2
	SCHEMBL2320748	0.90	MET (0.40)	JAK2JAK3METKDRMCHR1
	SCHEMBL2327583	0.89	MET (0.41)	JAK2JAK3METKDRCYP11B2
	SCHEMBL13968291	0.89	MET (0.39)	JAK2JAK3METKDRCYP11B2
	SCHEMBL2325268	0.89	PDK2 (0.42)	METPDK2
	SCHEMBL2327304	0.86	MET (0.40)	METKDRALKPDK2MAOB
	SCHEMBL2321729	0.84	MAPK1 (0.42)	JAK2JAK3KDRCYP11B2MAPK1
	SCHEMBL13968474	0.84	KDR (0.36)	METKDRCYP11B2CCNCCDK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.