SCHEMBL12439736

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2365126	0.94	BRAF (0.38)	MAPK1CYP11B2TRPV1KDRJAK2
	SCHEMBL2321729	0.91	MAPK1 (0.42)	MAPK1CYP11B2IKBKETBK1MKNK1
	SCHEMBL12440010	0.90	MAPK1 (0.44)	MAPK1CYP11B2IKBKETBK1MKNK1
	SCHEMBL13968442	0.89	MAPK1 (0.41)	MAPK1CYP11B2IKBKETBK1MKNK1
	SCHEMBL12441196	0.89	MAPK1 (0.41)	MAPK1CYP11B2IKBKETBK1MKNK1
	SCHEMBL13968290	0.88	MET (0.37)	MAPK1CYP11B2FGFR1FLT1FLT4
	SCHEMBL2325268	0.87	PDK2 (0.42)	FEN1ABL1PIK3CA
	SCHEMBL19791324	0.87	MAPK1 (0.39)	MAPK1CYP11B2IKBKETBK1MKNK1
	SCHEMBL2324722	0.87	CYP11B2 (0.40)	MAPK1CYP11B2IKBKETBK1MKNK1
	SCHEMBL2329554	0.86	MAPK1 (0.41)	MAPK1CYP11B2IKBKETBK1MKNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.