Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28238268 | 0.86 | ALOX15 (0.77) | ALOX15ALDH1A1PTPN7KMT2AMEN1 | |
| SCHEMBL473828 | 0.86 | CYP1A2 (0.78) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL127395 | 0.86 | CYP1A2 (0.78) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL43054 | 0.86 | CYP1A2 (0.78) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| Benzene SCHEMBL27779381 | 0.86 | CYP1A2 (0.78) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| Propionic Acid SCHEMBL15568852 | 0.84 | GAA (0.66) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL27637482 | 0.84 | CYP1A2 (0.57) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| Hydrochloric Acid SCHEMBL8691488 | 0.84 | CYP1A2 (0.75) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL18205114 | 0.84 | CYP1A2 (0.75) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL31540359 | 0.84 | CYP1A2 (0.75) | CYP1A2GAACYP2C9PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11371055-B2 | Herbicide resistance genes | CORTEVA AGRISCIENCE LLC (US) | 2022-06-28 | — | — | US | disclosed |
| US-10167483-B2 | Herbicide resistance genes | DOW AGROSCIENCES LLC (US) | 2019-01-01 | — | — | US | disclosed |
| CN-107177606-A | Novel herbicide resistance genes | 美国陶氏益农公司 | 2017-09-19 | — | — | CN | disclosed |
| US-20170211087-A1 | NOVEL HERBICIDE RESISTANCE GENES | PIONEER HI-BRED INTERNATIONAL, INC. | 2017-07-27 | — | — | US | disclosed |
| CN-101688219-B | Novel herbicide resistance gene | 美国陶氏益农公司 | 2017-06-30 | — | — | CN | disclosed |
| US-9624505-B2 | Uses and detection of herbicide resistance genes for resistance to aryloxyalkanoate herbicides | DOW AGROSCIENCES LLC (US) | 2017-04-18 | — | — | US | disclosed |
| US-20170009214-A9 | NOVEL HERBICIDE RESISTANCE GENES | PIONEER HI-BRED INTERNATIONAL, INC. | 2017-01-12 | — | — | US | disclosed |
| US-20160295862-A1 | METHODS OF IMPROVING THE YIELD OF 2,4-D RESISTANT CROP PLANTS | PIONEER HI-BRED INTERNATIONAL, INC. | 2016-10-13 | — | — | US | disclosed |
| US-20160002662-A1 | USES AND DETECTION OF HERBICIDE RESISTANCE GENES FOR RESISTANCE TO ARYLOXYALKANOATE HERBICIDES | PIONEER HI-BRED INTERNATIONAL, INC. | 2016-01-07 | — | — | US | disclosed |
| US-9062284-B2 | Uses and detection of herbicide resistance genes for resistance to aryloxyalkanoate herbicides | DOW AGROSCIENCES LLC (US) | 2015-06-23 | — | — | US | disclosed |
| US-20150080218-A1 | NOVEL HERBICIDE RESISTANCE GENES | DOW AGROSCIENCES LLC (US) | 2015-03-19 | — | — | US | disclosed |
| US-20150011513-A1 | ALKYNE-, AZIDE- AND TRIAZOLE-CONTAINING FLAVONOIDS AS MODULATORS FOR MULTIDRUG RESISTANCE IN CANCERS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2015-01-08 | — | — | US | disclosed |
| US-8916752-B2 | Herbicide resistance genes | DOW AGROSCIENCES, LLC (US) | 2014-12-23 | — | — | US | disclosed |
| US-20130260995-A1 | METHODS OF IMPROVING THE YIELD OF 2,4-D RESISTANT CROP PLANTS | CORTEVA AGRISCIENCE LLC | 2013-10-03 | — | — | US | disclosed |
| US-20130040815-A1 | USES AND DETECTION OF HERBICIDE RESISTANCE GENES FOR RESISTANCE TO ARYLOXYALKANOATE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-02-14 | — | — | US | disclosed |
| US-20130035233-A1 | NOVEL HERBICIDE RESISTANCE GENES | DOW AGROSCIENCES LLC (US) | 2013-02-07 | — | — | US | disclosed |
| US-8283522-B2 | Herbicide resistance genes | DOW AGROSCIENCES, LLC. (US) | 2012-10-09 | — | — | US | disclosed |
| US-8278505-B2 | Herbicide resistance genes for resistance to aryloxyalkanoate herbicides | DOW AGROSCIENCES, LLC. (US) | 2012-10-02 | — | — | US | disclosed |
| US-20110203017-A1 | Novel Herbicide Resistance Genes | DOW AGROSCIENCES, LLC (US) | 2011-08-18 | — | — | US | disclosed |
| US-20100251432-A1 | Novel Herbicide Resistance Genes | DOW AGROSCIENCES LLC (US) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110203017-A1 | Novel Herbicide Resistance Genes | AADAC, AGXT, DDT | ALOX15 1152/4885CYP1A2 119/4885GAA 297/4885 |
| US-20130040815-A1 | USES AND DETECTION OF HERBICIDE RESISTANCE GENES FOR RESISTANCE TO ARYLOXYALKANOATE HERBICIDES | AADAC, AGXT, HPD | ALOX15 945/4885CYP1A2 112/4885GAA 377/4885 |
| US-20150011513-A1 | ALKYNE-, AZIDE- AND TRIAZOLE-CONTAINING FLAVONOIDS AS MODULATORS FOR MULTIDRUG RESISTANCE IN CANCERS | ABCG2, ABCB1, ABCC1 | ALOX15 2035/4885CYP1A2 100/4885GAA 3383/4885 |
| US-20100251432-A1 | Novel Herbicide Resistance Genes | AADAC, AGXT, DDT | ALOX15 985/4885CYP1A2 126/4885GAA 343/4885 |
| US-20130035233-A1 | NOVEL HERBICIDE RESISTANCE GENES | AADAC, AGXT, DDT | ALOX15 1152/4885CYP1A2 119/4885GAA 297/4885 |
| US-20150080218-A1 | NOVEL HERBICIDE RESISTANCE GENES | AADAC, AGXT, DDT | ALOX15 1152/4885CYP1A2 119/4885GAA 297/4885 |
| US-20170009214-A9 | NOVEL HERBICIDE RESISTANCE GENES | AADAC, AGXT, DDT | ALOX15 1152/4885CYP1A2 119/4885GAA 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.