Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | GAA | P10253 | 1/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
| ▸ | PKM | P14618 | 1/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | PPARA | Q07869 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127395 | 1.00 | CYP1A2 (0.78) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| Benzene SCHEMBL27779381 | 1.00 | CYP1A2 (0.78) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL43054 | 1.00 | CYP1A2 (0.78) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL31540359 | 0.98 | CYP1A2 (0.75) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| Hydrochloric Acid SCHEMBL1961683 | 0.98 | CYP1A2 (0.75) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL18205114 | 0.98 | CYP1A2 (0.75) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| Hydrochloric Acid SCHEMBL8691716 | 0.98 | CYP1A2 (0.75) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| Hydrochloric Acid SCHEMBL8691488 | 0.98 | CYP1A2 (0.75) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL11842352 | 0.98 | CYP1A2 (0.75) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| Fluoride SCHEMBL28081187 | 0.98 | CYP1A2 (0.75) | CYP1A2GAACYP2C9PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1504002-B1 | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE BETA-AMINOKETONES AND OPTICALLY ACTIVE 1,3-AMINOALCOHOLS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2012-12-19 | — | — | EP | claimed |
| US-8324425-B2 | Method for producing bicyclic γ-amino acid derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-12-04 | — | — | US | claimed |
| US-20120071685-A1 | METHOD FOR PRODUCING BICYCLIC gamma-AMINO ACID DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-22 | — | — | US | claimed |
| CN-102356061-A | Method for producing bicyclic g-amino acid derivative | DAIICHI SANKYO CO LTD | 2012-02-15 | — | — | CN | claimed |
| EP-1971222-A2 | REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS | GENERAL MILLS, INC. (US) | 2008-09-24 | — | — | EP | claimed |
| WO-2007059066-A2 | REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS | GENERAL MILLS, INC. (US) | 2007-05-24 | — | — | WO | claimed |
| US-20070110844-A1 | REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS | GENERAL MILLS, INC. | 2007-05-17 | — | — | US | claimed |
| US-7161008-B2 | Optically active β-aminoketones, optically active 1,3-amino alcohols and processes for preparing them | Sanofi - Aventis Deutschland GmbH (DE) | 2007-01-09 | — | — | US | claimed |
| EP-1576194-B1 | BACTERIAL STRAINS OF DELFTIA ACIDOVORANS MC1-R, THEIR PRODUCTION AND THEIR USE IN THE PRODUCTION OF THE R ENANTIOMERS OF 2-PHENOXYPROPIONIC ACID DERIVATIVES | UFZ LEIPZIGHALLE GMBH (DE) | 2006-05-31 | — | — | EP | claimed |
| EP-1576147-B1 | BACTERIAL STRAINS DELFTIA ACIDOVORANS MC1-S, PRODUCTION AND USE THEREOF FOR THE PRODUCTION OF THE S ENANTIOMERS OF 2-PHENOXYPROPIONIC ACID DERIVATIVES | UFZ LEIPZIGHALLE GMBH (DE) | 2006-05-24 | — | — | EP | claimed |
| US-20040030145-A1 | Optically active B-aminoketones, optically active 1,3-amino alcohols and processes for preparing them | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-02-12 | — | — | US | claimed |
| EP-0862549-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE CARBOXYLIC ACIDS | UNION CARBIDE CHEM PLASTIC (US) | 2000-05-31 | — | — | EP | claimed |
| CN-1204314-A | Process for preparing optically active carboxylic acids | UNION CARBIDE CHEM PLASTIC (US) | 1999-01-06 | — | — | CN | claimed |
| EP-0862549-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE CARBOXYLIC ACIDS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-09-09 | — | — | EP | claimed |
| US-5739385-A | OXIDIZING AN OPTICALLY ACTIVE ALDEHYDE WITH A PERACID IN THE PRESENCE OF AN AMINE AND/OR AMINE N-OXIDE CATALYST | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-04-14 | — | — | US | claimed |
| WO-1997014669-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE CARBOXYLIC ACIDS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-04-24 | — | — | WO | claimed |
| EP-0159864-B1 | METHOD OF MODIFYING TASTE | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1989-07-19 | — | — | EP | claimed |
| EP-0159864-A2 | Method of modifying taste | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1985-10-30 | — | — | EP | claimed |
| JP-10175913-A | — | — | None | — | — | JP | disclosed |
| US-4518416-A | Certain trimethyl silyl-lower-alkyl esters of pyridyloxy-phenoxy-lower alkanoic acids, compositions containing same and herbicidal method of use | BAYER AKTIENGESELLSCHAFT (DE) | 1985-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071685-A1 | METHOD FOR PRODUCING BICYCLIC gamma-AMINO ACID DERIVATIVE | ADRA2A, GABRB2, ADRB2 | CYP1A2 96/4885GAA 1160/4885CYP2C9 249/4885 |
| US-20040030145-A1 | Optically active B-aminoketones, optically active 1,3-amino alcohols and processes for preparing them | ORMDL3, OR10J3, BCAT2 | CYP1A2 429/4885GAA 3204/4885CYP2C9 1605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.