Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 4/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108962 | 0.89 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL5698950 | 0.85 | TSHR (0.68) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL140103 | 0.83 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL5698934 | 0.82 | TSHR (0.69) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL107385 | 0.82 | TSHR (0.47) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL1331857 | 0.79 | — | — | |
| SCHEMBL5681395 | 0.79 | TSHR (1.00) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL1330627 | 0.79 | — | — | |
| SCHEMBL15037 | 0.79 | — | — | |
| SCHEMBL11582291 | 0.79 | TSHR (1.00) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279441-A1 | RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2024-08-22 | — | — | US | disclosed |
| EP-4349902-A1 | RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2024-04-10 | — | — | EP | disclosed |
| US-11530318-B2 | Rubber composition and pneumatic tire | BRIDGESTONE CORPORATION (JP) | 2022-12-20 | — | — | US | disclosed |
| WO-2022254751-A1 | RUBBER COMPOSITION AND TIRE | 株式会社ブリヂストン | 2022-12-08 | — | — | WO | disclosed |
| EP-3725836-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2022-08-24 | — | — | EP | disclosed |
| US-9745406-B2 | Curable composition | CEMEDINE CO., LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| EP-2412756-B1 | CURABLE COMPOSITION | CEMEDINE CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| EP-2412756-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-20120004371-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |
| EP-1149866-A2 | Rubber mixtures based on crosslinked rubber particles and non-crosslinked rubbers | JSR Corporation (JP) | 2001-10-31 | — | — | EP | disclosed |