SCHEMBL107385

SCHEMBL107385

C=CC(=O)OC[SiH](OCC)OCC

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.47
HPGD P15428 1/20 0.47
ALDH1A1 P00352 7/20 0.42
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
CYP3A4 P08684 2/20 0.42
HSD17B10 Q99714 2/20 0.42
THRB P10828 4/20 0.40
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HCAR2 Q8TDS4 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108962 0.85 TSHR (0.53) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28464042 0.84 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL236552 0.82 TSHR (0.65) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL238023 0.81 TSHR (0.53) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28453703 0.81 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2584600 0.79 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL551679 0.78 HCAR2 (0.39) ALDH1A1HCAR2NPSR1
SCHEMBL81412 0.78 TSHR (0.59) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5406660 0.77 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL110716 0.77 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4035649-B1 DENTAL ADHESIVE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-07-26 EP claimed
EP-4035649-A1 DENTAL ADHESIVE COMPOSITION 3M Innovative Properties Company (US) 2022-08-03 EP claimed
EP-3310792-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-07-21 EP claimed
CN-109266079-A A kind of ACS doping inorganic nano fungicidal paint and preparation method thereof 湖南凯斯利新材料有限公司 2019-01-25 CN claimed
US-20010053813-A1 Rubber compositions JSR CORPORATION (JP) 2001-12-20 US claimed
EP-4747320-A1 THERMAL-AND UV-CURABLE (METH) ACRYLATE COMPOSITION Henkel AG & Co. KGaA (DE) 2026-05-27 EP disclosed
US-20260139157-A1 THERMAL-AND-UV-CURABLE (METH)ACRYLATE COMPOSITION HENKEL AG & CO KGAA (DE) 2026-05-21 US disclosed
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-29 US disclosed
US-12319815-B2 Resin composition, method for producing same, and multi-liquid curable resin composition KANEKA CORPORATION (JP) 2025-06-03 US disclosed
US-12312494-B2 Resin composition, method for producing same, and multi-liquid curable resin composition KANEKA CORPORATION (JP) 2025-05-27 US disclosed
CN-114829430-B Curable composition comprising a multistage polymer 阿科玛法国公司 2025-04-22 CN disclosed
CN-119584936-A Curable composition for producing transparent orthodontic accessories 舒万诺知识产权公司 2025-03-07 CN disclosed
EP-1325946-A2 Coating composition for the protection of packaging and interconnecting boards SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-07-09 EP disclosed
US-6448427-B1 REACTING AN ALKALI-METAL SALT OF (METH)ACRYLIC ACID WITH A HALOGEN SUBSTITUTED ORGANOSILICON COMPOUND IN THE PRESENCE OF A TERTIARY AMINE DIAZABICYCLO DERIVATIVE DOW CORNING TORAY SILICONE CO., LTD. (JP) 2002-09-10 US disclosed
EP-1234830-A2 Method of preparing an organosilicon compound containing a methacryloxy functional group Dow Corning Toray Silicone Co., Ltd. (JP) 2002-08-28 EP disclosed
US-20020115878-A1 METHOD OF PREPARING AN ORGANOSILICON COMPOUND CONTAINING A METHACRYLOXY FUNCTIONAL GROUP DOW TORAY CO., LTD. (JP) 2002-08-22 US disclosed
EP-0486279-B2 Process for removing acidic impurities from alkoxysilanes SHINETSU CHEMICAL CO (JP) 1999-12-01 EP disclosed
US-5502096-A POLYSILOXANES OR POLYETHERS FOR CURABLE RUBBER POLYMERS BOTH HAVING SILYL BLOCKING GROUPS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-03-26 US disclosed
US-5247117-A Neutralization with sterically hindered alcohols or amines, distillation SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-09-21 US disclosed
EP-0486279-A1 Process for removing acidic impurities from alkoxysilanes SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SMCHD1, SMC2, SMC1A TSHR 705/4885HPGD 4304/4885ALDH1A1 1413/4885
US-20260139157-A1 THERMAL-AND-UV-CURABLE (METH)ACRYLATE COMPOSITION MAT1A, MAT2B, MAT2A TSHR 2841/4885HPGD 2616/4885ALDH1A1 139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.