Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL595243 | 0.72 | ATM (0.69) | POLBTSHRKDM4EATMKMT2A | |
| SCHEMBL23220443 | 0.71 | MAPT (0.47) | POLBKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL7907173 | 0.69 | POLB (0.57) | POLBTSHRKDM4EATMKMT2A | |
| Urethane SCHEMBL28839463 | 0.68 | MAOA (0.58) | POLBTSHRKDM4EATMKMT2A | |
| SCHEMBL18516738 | 0.68 | KMT2A (0.34) | POLBTSHRKDM4EKMT2AMEN1 | |
| SCHEMBL4822281 | 0.67 | TSHR (0.54) | POLBTSHRKDM4EKMT2AMEN1 | |
| SCHEMBL14193348 | 0.67 | TSHR (0.54) | POLBTSHRKDM4EKMT2AMEN1 | |
| SCHEMBL9545140 | 0.67 | POLB (0.51) | POLBTSHRKDM4EATMKMT2A | |
| SCHEMBL30280555 | 0.67 | TSHR (0.47) | POLBTSHRKDM4EATMKMT2A | |
| SCHEMBL6204083 | 0.66 | KCNE1 (0.38) | ATMKMT2AMEN1LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3334713-B1 | PHENYLSULFONAMIDO-BENZOFURAN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF PROLIFERATIVE DISEASES | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2021-07-21 | — | — | EP | disclosed |