Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.32 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365457 | 0.84 | LIPE (0.36) | TEAD1TEAD3PPARDPPARA | |
| SCHEMBL2365397 | 0.83 | TEAD1 (0.32) | TEAD1TEAD3PPARGPPARDPPARA | |
| SCHEMBL2365569 | 0.82 | KCNA5 (0.36) | TEAD1TEAD3PPARGPPARDPPARA | |
| SCHEMBL2363761 | 0.82 | S1PR5 (0.41) | — | |
| SCHEMBL2365562 | 0.81 | FFAR1 (0.37) | TEAD1TEAD3PPARGPPARDPPARA | |
| SCHEMBL2365496 | 0.80 | TEAD1 (0.36) | TEAD1TEAD3MEN1KMT2A | |
| SCHEMBL2365540 | 0.78 | GRIN2B (0.42) | TEAD1TEAD3 | |
| SCHEMBL2365258 | 0.78 | ACKR3 (0.42) | TEAD1TEAD3PPARDPPARA | |
| SCHEMBL2365409 | 0.74 | POLB (0.38) | MEN1KMT2A | |
| SCHEMBL2365536 | 0.67 | LIPE (0.36) | TEAD1TEAD3PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | claimed |
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |