Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 11/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365457 | 0.86 | LIPE (0.36) | — | |
| SCHEMBL2365496 | 0.85 | TEAD1 (0.36) | — | |
| SCHEMBL2363075 | 0.83 | S1PR5 (0.40) | S1PR5S1PR1S1PR3TP53TSHR | |
| SCHEMBL2365258 | 0.83 | ACKR3 (0.42) | — | |
| SCHEMBL2365539 | 0.82 | TEAD1 (0.32) | — | |
| SCHEMBL2365562 | 0.81 | FFAR1 (0.37) | — | |
| SCHEMBL2363762 | 0.77 | GPR119 (0.47) | S1PR5HRH2HRH1 | |
| SCHEMBL2365409 | 0.75 | POLB (0.38) | TSHRL3MBTL1 | |
| SCHEMBL2365423 | 0.69 | LTA4H (0.35) | — | |
| SCHEMBL2365494 | 0.69 | ACKR3 (0.45) | HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | claimed |
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |