Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.32 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365397 | 0.83 | TEAD1 (0.32) | MEN1KMT2ATEAD1TEAD3PPARG | |
| SCHEMBL2365539 | 0.82 | TEAD1 (0.32) | MEN1KMT2ATEAD1TEAD3PPARG | |
| SCHEMBL2365494 | 0.81 | ACKR3 (0.45) | HRH2HRH1TEAD1TEAD3PPARD | |
| SCHEMBL2363548 | 0.80 | KDM4E (0.43) | TEAD1TEAD3LTA4H | |
| SCHEMBL2364770 | 0.80 | GPR119 (0.41) | KCNA5HRH2HRH1TEAD1TEAD3 | |
| SCHEMBL2365577 | 0.80 | HRH2 (0.37) | KCNA5HRH2HRH1MEN1KMT2A | |
| SCHEMBL2231126 | 0.78 | GRIN2B (0.44) | KCNA5HRH2HRH1TEAD1TEAD3 | |
| SCHEMBL2365541 | 0.74 | GAA (0.39) | MEN1KMT2AUSP2 | |
| SCHEMBL2363554 | 0.71 | HTR7 (0.36) | LTA4H | |
| SCHEMBL2365258 | 0.69 | ACKR3 (0.42) | TEAD1TEAD3HRH3PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |