Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130140 | 0.86 | CYP3A4 (0.59) | ELANELMNACYP3A4MAPTPOLB | |
| 4-Acetoxyphenol SCHEMBL203149 | 0.83 | LMNA (0.67) | ELANELMNACYP3A4MAPTPOLB | |
| SCHEMBL23176192 | 0.82 | ELANE (0.47) | ELANELMNACYP3A4MAPTPOLB | |
| 4-Acetoxyphenol SCHEMBL27952470 | 0.81 | LMNA (0.64) | ELANELMNACYP3A4MAPTPOLB | |
| 4-Acetoxyphenol SCHEMBL27671868 | 0.81 | LMNA (0.64) | ELANELMNACYP3A4MAPTPOLB | |
| SCHEMBL25732393 | 0.80 | ELANE (0.49) | ELANELMNACYP3A4MAPTPOLB | |
| SCHEMBL10057842 | 0.80 | ESR1 (0.65) | ELANELMNACYP3A4MAPTPOLB | |
| SCHEMBL10504945 | 0.80 | LMNA (0.57) | ELANELMNACYP3A4MAPTPOLB | |
| SCHEMBL4449332 | 0.79 | ESR1 (0.62) | LMNACYP3A4MAPTHSD17B10MEN1 | |
| SCHEMBL11724586 | 0.78 | SHBG (0.50) | ELANELMNACYP3A4MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3851495-A1 | THERMOPLASTIC POLYCARBONATE COMPOSITIONS WITH IMPROVED HYDROLYTIC STABILITY AND ELECTRICAL TRACKING RESISTANCE AND SHAPED ARTICLES THEREOF | SHPP Global Technologies B.V. (NL) | 2021-07-21 | — | — | EP | disclosed |