SCHEMBL23655822

SCHEMBL23655822

CCCc1nc2ccc(Cl)cn2c1C=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PABPC1 P11940 1/20 0.51
ALDH1A1 P00352 2/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
TSPO P30536 2/20 0.39
NR1I2 O75469 1/20 0.39
ABCB11 O95342 1/20 0.39
ALB P02768 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
ADORA1 P30542 1/20 0.39
OPRM1 P35372 1/20 0.39
DRD3 P35462 1/20 0.39
OPRK1 P41145 1/20 0.39
PDE4D Q08499 1/20 0.39
KCNH2 Q12809 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
GABRA2 P47869 1/20 0.37
GABRB2 P47870 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12294859 0.88 ALDH1A1 (0.42) PABPC1ALDH1A1POLBGAATSPO
SCHEMBL15266482 0.77 ALDH1A1 (0.51) ALDH1A1POLBGAACYP1A2CYP2C9
SCHEMBL7913154 0.77 PARP1 (0.42) ALDH1A1POLBGAACYP1A2CYP2C9
SCHEMBL6101878 0.74 PABPC1 (0.56) PABPC1ALDH1A1POLBGAATSPO
SCHEMBL7655591 0.72 ALDH1A1 (0.52) ALDH1A1GAATSPONR1I2ABCB11
SCHEMBL19116278 0.71 NPC1 (0.55) PABPC1ALDH1A1POLBGAAPKM
SCHEMBL12844547 0.70 PABPC1 (0.52) PABPC1ALDH1A1POLBGAATSPO
SCHEMBL9203119 0.70 PABPC1 (0.43) PABPC1ALDH1A1POLBGAATSPO
SCHEMBL1430433 0.70 CYP1A2 (0.52) ALDH1A1GAACYP1A2CYP2C9CYP2C19
SCHEMBL23655363 0.69 ALDH1A1 (0.46) PABPC1ALDH1A1POLBGAATSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3027615-B1 ANTI-INFECTIVE COMPOUNDS PASTEUR INSTITUT KOREA (KR) 2021-07-21 EP disclosed