Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15266482 | 0.83 | ALDH1A1 (0.51) | PARP1ALDH1A1GAAPOLBPIK3CD | |
| SCHEMBL7655591 | 0.80 | ALDH1A1 (0.52) | MAPTKDM4EALDH1A1GAASLC2A1 | |
| SCHEMBL12294859 | 0.79 | ALDH1A1 (0.42) | PARP1ALDH1A1GAAPOLBGABRA2 | |
| SCHEMBL29955989 | 0.78 | MAPT (0.63) | PARP1MAPTKDM4ENPSR1ALDH1A1 | |
| SCHEMBL1430433 | 0.78 | CYP1A2 (0.52) | KDM4EALDH1A1GAASLC2A1NPC1 | |
| SCHEMBL23655822 | 0.77 | PABPC1 (0.51) | PARP1ALDH1A1GAAPOLBGABRA2 | |
| SCHEMBL15330868 | 0.76 | ALDH1A1 (0.63) | MAPTKDM4EALDH1A1GAASLC2A1 | |
| SCHEMBL29953217 | 0.76 | ALDH1A1 (0.52) | KDM4EALDH1A1GAASLC2A1NPC1 | |
| SCHEMBL15332057 | 0.76 | ALDH1A1 (0.46) | MAPTKDM4EALDH1A1GAASLC2A1 | |
| SCHEMBL1664765 | 0.75 | KDM4E (0.64) | MAPTKDM4ENPSR1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-6214801-B1 | INHIBITION OF DNA OR RNA VIRAL PROLIFERATION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2001-04-10 | — | — | US | disclosed |
| WO-1997027205-A1 | IMIDAZO[1,2-A]PYRIDINE C-NUCLEOSIDES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1997-07-31 | — | — | WO | disclosed |
| EP-0383319-A2 | Imidazopyridines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-08-22 | — | — | EP | disclosed |