Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8363020 | 0.93 | LMNA (0.49) | SLC18A3SMN1; SMN2HSD17B10HPGDMAPT | |
| SCHEMBL7446491 | 0.87 | MBTD1 (0.55) | SLC18A3MBTD1L3MBTL3L3MBTL1SMN1; SMN2 | |
| SCHEMBL10035921 | 0.83 | MAPT (0.49) | SLC18A3L3MBTL1SMN1; SMN2HSD17B10NPC1 | |
| SCHEMBL16763481 | 0.82 | SLC18A3 (0.47) | SLC18A3MBTD1L3MBTL3L3MBTL1SMN1; SMN2 | |
| SCHEMBL17481525 | 0.81 | TRPV6 (0.54) | SMN1; SMN2NPC1RAB9AMAPTDRD2 | |
| SCHEMBL16447503 | 0.80 | SLC18A3 (0.43) | SLC18A3L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL17876411 | 0.79 | KDM4E (0.49) | SLC18A3TP53ADRB1ALDH1A1 | |
| SCHEMBL6678742 | 0.79 | SLC18A3 (0.42) | SLC18A3L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL171804 | 0.78 | MAPT (0.62) | SMN1; SMN2HSD17B10NPC1RAB9AMAPT | |
| SCHEMBL20346979 | 0.78 | MEN1 (0.45) | SLC18A3MBTD1L3MBTL3L3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027615-B1 | ANTI-INFECTIVE COMPOUNDS | PASTEUR INSTITUT KOREA (KR) | 2021-07-21 | — | — | EP | disclosed |