Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARHGEF12 | Q9NZN5 | 1/20 | 0.69 |
| ▸ | CTSL | P07711 | 2/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RGS12 | O14924 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20175987 | 0.82 | ARHGEF12 (1.00) | ARHGEF12GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL19665210 | 0.82 | ARHGEF12 (1.00) | ARHGEF12GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL29372342 | 0.82 | ARHGEF12 (1.00) | ARHGEF12GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL17603571 | 0.82 | ARHGEF12 (1.00) | ARHGEF12GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL15936925 | 0.82 | ARHGEF12 (1.00) | ARHGEF12GAAMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL31717447 | 0.81 | ARHGEF12 (0.98) | ARHGEF12GAAMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL29557944 | 0.81 | ARHGEF12 (0.98) | ARHGEF12GAAMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL29557889 | 0.81 | ARHGEF12 (0.98) | ARHGEF12GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL9025972 | 0.76 | CTSL (0.76) | CTSLCTSSCTSKMAPTSMN1; SMN2 | |
| SCHEMBL14300166 | 0.76 | CTSL (0.76) | CTSLCTSSCTSKMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021146343-A1 | PLATELET STORAGE METHODS AND COMPOSITIONS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2021-07-22 | — | — | WO | disclosed |