Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 10/20 | 0.65 |
| ▸ | PARP11 | Q9NR21 | 10/20 | 0.65 |
| ▸ | GRM5 | P41594 | 4/20 | 0.61 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 2/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | FER | P16591 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL279903 | 0.79 | PARP10 (1.00) | PARP10PARP11GRM5PARP1PDPK1 | |
| SCHEMBL29978302 | 0.79 | PARP10 (1.00) | PARP10PARP11GRM5PARP1PDPK1 | |
| SCHEMBL8156296 | 0.79 | PARP10 (1.00) | PARP10PARP11GRM5PARP1PDPK1 | |
| SCHEMBL24783703 | 0.78 | PARP10 (0.63) | PARP10PARP11GRM5MKNK1PARP1 | |
| SCHEMBL23657096 | 0.78 | MAPK14 (0.69) | GRM5MAPK14 | |
| SCHEMBL504553 | 0.76 | GRM5 (1.00) | PARP10PARP11GRM5PARP1 | |
| SCHEMBL552293 | 0.75 | PARP10 (0.58) | PARP10PARP11GRM5MKNK1PARP1 | |
| SCHEMBL13558414 | 0.75 | NPSR1 (0.58) | MAPK14 | |
| SCHEMBL23432222 | 0.74 | PARP10 (0.58) | PARP10PARP11GRM5MKNK1PARP1 | |
| SCHEMBL25124551 | 0.74 | PARP10 (0.58) | PARP10PARP11GRM5MKNK1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348401-A1 | Inhibitors of Glucose-6-phosphate Dehydrogenase and Uses Thereof | THE TRUSTEES OF PRINCETON UNIVERSITY | 2023-11-02 | — | — | US | disclosed |
| WO-2021146543-A1 | INHIBITORS OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE AND USES THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2021-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348401-A1 | Inhibitors of Glucose-6-phosphate Dehydrogenase and Uses Thereof | G6PD, UGDH, GPI | PARP10 1184/4885PARP11 1435/4885GRM5 1633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.