Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657120 | 0.86 | GAA (0.50) | ALDH1A1CYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL19974430 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL19974431 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL19981496 | 0.82 | LMNA (0.50) | ALDH1A1CYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL25100407 | 0.73 | CNR1 (0.44) | ALDH1A1LMNAGSTO1RAB9AKDM4E | |
| SCHEMBL19981509 | 0.70 | ALDH1A1 (0.55) | ALDH1A1CYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL2538900 | 0.70 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL23647317 | 0.69 | LMNA (0.50) | ALDH1A1CYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL19981501 | 0.67 | LMNA (0.48) | ALDH1A1CYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL330837 | 0.67 | XIAP (0.43) | CYP1A2RAB9ARXFP1XIAPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11597708-B2 | Inhibitors of heat shock factors and uses thereof | HSF PHARMACEUTICALS SA (CH) | 2023-03-07 | — | — | US | disclosed |
| US-20210221778-A1 | Inhibitors of heat shock factors and uses thereof | HSF PHARMACEUTICALS SA (CH) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11597708-B2 | Inhibitors of heat shock factors and uses thereof | HSF1, HSP90AB2P, HSP90AB1 | ALDH1A1 2641/4885CYP1A2 4682/4885CYP2C9 4815/4885 |
| US-20210221778-A1 | Inhibitors of heat shock factors and uses thereof | HSF1, HSP90AB2P, HSP90AB1 | ALDH1A1 2641/4885CYP1A2 4682/4885CYP2C9 4815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.